These are options to make it easier to continue with your diet and exercise.
Medical therapy in medical dieting is not for "getting thin with medication alone."
The basics of weight management are diet, lifestyle, and exercise.
However, if you have difficulty controlling your appetite, large blood sugar fluctuations, find it difficult to lose weight through diet and exercise alone, or have repeatedly regained weight, medication may be an option.
At Ikenjiri Ohashi Sera Clinic, doctors review your weight, body fat, muscle mass, blood sugar, liver function, kidney function, medical history, current medications, and more before proposing drug therapy as needed.
Main medications handled at our hospital
Our medical diet program primarily uses the following medications:
Ruyfene (SGLT2 inhibitor)
・ Rybelsus (GLP-1 receptor agonist)
・Mounjaro (GIP/GLP-1 receptor agonist)
Since the effects and precautions differ for each drug, a doctor will make a judgment based on your physical condition and objectives.
Rusefi
Rusefi is an oral medication of the SGLT2 inhibitor class.
This medicine suppresses the reabsorption of sugar in the kidneys, making it easier to excrete excess sugar in urine.
Regarding weight loss,By excreting sugar in the urine, energy is lost from the body.is the main mechanism.
This is not a medication that directly suppresses appetite, but in individuals with high blood sugar, weight loss may be observed along with improvements in blood sugar levels.
We will consider candidates with this profile.
・People with high blood sugar levels
For those who want to manage their weight from a blood sugar and metabolic perspective, rather than through appetite suppressants
Those who wish to be treated with oral medication
important point
Sugar in your urine can cause increased urination and thirst.
Additionally, attention should be paid to dehydration, urinary tract infections, genital infections, increased ketone bodies in the blood, and ketoacidosis. Careful judgment is required, especially for those on extreme carbohydrate restriction, those with low food intake, and those prone to dehydration.
Rybelsus
Reblis is an oral medication belonging to a class of drugs called GLP-1 receptor agonists.
GLP-1 is one of the hormones secreted by the intestines after a meal. It helps to secrete insulin in response to blood sugar levels, slows down stomach motility, and plays a role in appetite regulation.
For weight loss, primarilyEasier to feel full, easier to eat lessis related.
This is an option for those who "snack a lot," "want to reduce meal portions but suffer from hunger," or "find it difficult to control their appetite."
Rebyrsub is a once-daily oral medication. It should be taken with a small amount of water on an empty stomach after waking up, and you should avoid eating, drinking, or taking other medications for a while afterward. This medication's effectiveness can be easily affected by how it is taken.
We will consider candidates with this profile.
・Those who have difficulty controlling their appetite
Those who want to reduce their food intake without overdoing it
Those who prefer oral medication over injections
・People with high blood sugar levels
For those who want to start with oral medication that is not as strong as Mounjaro
important point
The main side effects are gastrointestinal symptoms such as nausea, diarrhea, constipation, and abdominal discomfort.
Also, caution is needed for hypoglycemia, acute pancreatitis, cholecystitis, cholangitis, ileus, and other conditions.
Mounjaro
Mounjaro is a weekly injectable medication that is part of a class of drugs called GIP/GLP-1 receptor agonists.
The major difference from Rybelsus is that it acts on not only the GLP-1 receptor but also the GIP receptor.
For weight loss,Appetite control, reduced food intake, blood sugar improvement, effect on metabolismthings like that are involved.
It tends to have a stronger weight loss effect than Rybelsus, but it is an injectable formulation, so you will need to administer the injections yourself.
We will consider candidates with this profile.
Those who find it difficult to control their appetite
Individuals for whom oral medications are unlikely to be sufficiently effective
For those who want to lose weight more effectively
・People with high blood sugar levels
Those who wish to be treated with a weekly injection
important point
The main side effects are nausea, vomiting, diarrhea, constipation, abdominal pain, indigestion, and loss of appetite.
In addition, caution is necessary for hypoglycemia, acute pancreatitis, cholecystitis, ileus, injection site reactions, and other issues.
While a loss of appetite can make it easier to lose weight, drastically reducing food intake can lead to a loss of muscle mass and nutritional deficiencies. It is important to proceed while monitoring not only your weight but also your muscle mass, dietary content, and physical condition.
What's important in drug therapy
Even when undergoing drug therapy, it is necessary to review diet and lifestyle habits.
Medications can make it easier to control appetite and blood sugar, but if your diet is significantly disordered or muscle mass is declining, it can be difficult to achieve sufficient effects and may lead to rebound weight gain.
With GLP-1 receptor agonists and GIP/GLP-1 receptor agonists in particular, while food intake decreases, insufficient protein intake and maintenance of muscle strength can lead to a loss of muscle mass.
At our clinic, we also incorporate exercise programs by physical therapists as needed, and proceed while checking not only weight but also muscle mass and physical condition.
About Private Payment Medical Care
Medically necessary examinations and consultations for conditions such as diabetes, dyslipidemia, fatty liver, and thyroid disease may be covered by health insurance.
On the other hand, Rybelsus, Mounjaro, and Rybelsus are all approved drugs for type 2 diabetes in Japan, and their use for weight loss purposes will be under private medical care.
The cost for one month's supply when prescribed as private medical treatment is as follows:
| GLP-1 oral (Reversus 3mg) | 9,800 yen (tax included) |
| GLP-1 oral (Reversus 7 mg) | 19.800 yen (tax included) |
| GLP-1 oral (Reversus 14 mg) | 29,800 yen (tax included) |
| GIP and GLP-1 injection (Manjaro 2.5 mg) | 22,000 yen (tax included) |
| GIP and GLP-1 injection (Manjaro 5mg) | 44,000 yen (tax included) |
| GIP and GLP-1 injection (Manjaro 7.5 mg) | 66,000 yen (tax included) |
| SGLT2 inhibitor (Rocefy 2.5 mg) | 11,000 yen (tax included) |
Please consult with a doctor first.
Medical diet drug therapy involves different medications suited to your constitution, existing conditions, blood test results, and lifestyle.
"Which medicine is best for weight loss?" instead of
"Does it suit your current physical condition?"
Is it safe to continue?
Can I prevent rebound by combining it with diet and exercise?
It is important to consider.
At Ikenjiri Ohashi Sera Clinic, after a physician's medical evaluation, we propose a combination of pharmacotherapy, dietary and lifestyle modifications, and exercise programs as needed.
If you're struggling with your own diet, have difficulty controlling your appetite, or have been told by your doctor that you have abnormal blood sugar, lipids, or liver function, please feel free to consult us via web reservation under "Medical Diet."
Feel free to reach out during your physical therapy appointments or other check-ups.
Frequently Asked Questions (FAQ)
A. Can I lose weight without dieting or exercising if I use medication?
Yes, medication can help control appetite and make it easier to lose weight.
However, diet, lifestyle habits, and maintaining muscle mass are also important.
A. How long does it take to see results?
While individual results may vary, many people notice changes in their weight and appetite within a few weeks.
With Rybelsus and Mounjaro, you start with a low dose and gradually adjust it, so we proceed while checking the effects.
We focus on a pace that can be safely maintained, rather than rapid, short-term weight loss.
How long do I need to continue?
A. It depends on your target weight, physical condition, the effectiveness of medication, side effects, and changes in lifestyle.
We will discuss continuing, reducing, or stopping treatment based on progress observed over several months.
While using medication, it is important to maintain a regular diet and exercise routine.
Is drug therapy safe?
A. A physician will conduct a consultation and examinations, and will use it after confirming pre-existing conditions, oral medications, blood sugar levels, liver function, kidney function, etc.
However, all medications have side effects.
With Rybelsus and Mounjaro, you need to be careful about side effects such as nausea, constipation, and diarrhea. With Rybelsus, you need to be careful about dehydration and urinary tract infections.
Depending on your physical constitution or pre-existing health conditions, you may not be able to use it.
Will I experience withdrawal symptoms if I stop taking the medication?
After stopping medication, appetite and food intake may return, which can lead to weight gain.
Therefore, we recommend gradually reducing your medication rather than stopping it abruptly after you've lost weight, so you can maintain your weight.
Also, it's important to maintain a balanced diet, regular daily routine, and exercise habits while taking medication.